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Dermatology

Rejuran is four different products, and clinics rarely say which one you booked

Written by KCODI medical interpreter team · English deskUpdated · 8 min read
A pharmacist in a white coat handing a paper medicine bag across the counter to a customer (illustrative image)

A rejuran treatment is one of the most-booked appointments foreigners make in Seoul, and one of the least explained. You book Rejuran, you get injected, you leave with small bumps and a vague sense that something good happened.

What almost nobody is told is that the name covers a family of products. They share the same base material, a polynucleotide derived from salmon DNA, but they differ in concentration, in what else is in the syringe, and in where in the skin they belong.

Booking the wrong one is not dangerous. It is simply a wasted appointment and a wasted week of your trip. Here is how the versions differ and what to ask before the needle is drawn up.

The four names on a Seoul menu

How Korean clinics generally use each version. Your doctor decides what suits your skin.
VersionGenerally used forDepth and techniqueWhat patients notice
HealerOverall skin quality, fine lines, the classic first courseMany small injections across the faceBumps that settle over a day or so
HBSkin that also needs hydration; blended with hyaluronic acidSimilar technique, softer feel afterwardsLess bumpy, more immediate plumpness
iThe thin skin around the eyesShallow, very small volumesBruising here is more likely than elsewhere
SFocal work on scars and textureTargeted rather than spread across the faceSlower, judged over a course

Clinics mix and match within a single appointment, which is reasonable. What is not reasonable is not telling you which was used, especially when you are comparing the price against a quote from another clinic that used a different version.

One practical consequence: two quotes that look far apart are often quoting different versions in different volumes, and neither menu says so. Asking for the version and the syringe count turns two mystery numbers into a comparison you can actually make, and it takes about ten seconds at the counter.

It is also worth knowing that clinics in Seoul buy these products at different prices depending on volume, so the same version genuinely does cost different amounts in two buildings on the same street. That is ordinary commerce rather than a trap, and it is why the partner rate matters more than a promotion.

The current range partner clinics work in is on the Rejuran and skin boosters page, and how this product sits against other boosters is in Korean skin boosters compared.

What a rejuran injection actually does

It is not a filler. Nothing is being added for volume and nothing lifts on the day. The material is placed into the skin to prompt repair, and what you are buying is your own skin's response over the following weeks.

That has two consequences people find annoying. The first is that a single session shows very little. Courses are the norm, spaced a few weeks apart, which is awkward for a visitor. The second is that the result is a change in skin quality rather than a change in shape, so photographs rarely capture it and the person who notices first is usually you, in the mirror, at week four.

Who it suits, and who should spend the money elsewhere

  • Thin, crepey skin that looks tired rather than lined. This is the best fit.
  • Skin that has been over-treated with lasers and needs a repair phase rather than another aggressive session.
  • Under-eye texture, where the i version is used and where expectations need to be lowest.
  • Post-acne texture as part of a longer plan, not as the whole plan.

It is a poor choice for volume loss, for sagging that needs lifting, and for deep indented scars, all of which need a different intervention. It is also a poor choice when acne is active. Pigment is a different problem again and belongs with the treatments on the pigmentation and laser page.

Pregnancy, breastfeeding and active skin infection are the usual reasons a doctor will decline, and a history of keloid scarring is worth mentioning because any needle is an injury. If you are taking anything that affects bleeding, say so, because bruising after dozens of small injections is the difference between a good week and a covered-up one.

If your skin is dry rather than thin, the version question matters even more, and the best PDRN in Korea for dry skin goes through that specific decision.

What the appointment is like and what follows it

Numbing cream goes on for around twenty to thirty minutes. The injections themselves take ten to fifteen. It stings more than filler and less than most people fear. Afterwards the face carries small raised bumps where the product sits.

  1. Bumps generally settle within a day, sometimes two. Do not book it the morning of an event.
  2. Bruising is possible anywhere and likelier under the eyes. Arnica does not prevent it; planning does.
  3. Skip saunas, alcohol and hard exercise that day, which in Seoul mostly means skipping the jjimjilbang.
  4. Keep the skin simple for a couple of days: no acids, no retinoids, no scrubs.
  5. Sunscreen, which is the boring instruction everybody drops while sightseeing.
A quiet hotel room near a Seoul clinic used for the evening after an injectable appointment (illustrative image)
Book it on a low-key evening. The bumps are brief but they are visible.

If you are only in Korea once, say so. A doctor planning a single session chooses differently from one planning a course of four, and the honest version of that conversation is worth more than a discounted package you will never finish. For the whole menu side by side, see Korean skin treatments compared or let clinic matching shortlist for you.

Questions patients ask us

What is Rejuran?
It is a Korean injectable made from polynucleotides derived from salmon DNA, placed into the skin to prompt repair rather than to add volume. It is sold in several versions that differ in concentration and in what else is in the syringe.
What is the difference between Rejuran Healer, HB, i and S?
Healer is the standard version used across the face. HB blends in hyaluronic acid for skin that also needs hydration. The i version is formulated for the thin skin around the eyes. S is used for focal work on scars and texture. Your doctor chooses based on what your skin needs, and you should be told which one was used.
How many sessions do I need?
Courses are the norm rather than single visits, usually spaced a few weeks apart. Ask what one session alone is expected to achieve, since that may be all your trip allows, and get the answer before you pay for a package.
Does a rejuran injection hurt?
It stings more than filler. Numbing cream for twenty to thirty minutes beforehand is standard in Korean clinics; confirm it is included rather than an added line on the bill.
How long do the bumps last?
Usually under a day, sometimes into a second day, and longer under the eyes. Plan the appointment for an evening you have nothing on rather than the day of a dinner.
Can I have it with laser or a facial on the same day?
Only if a doctor has planned the combination. Stacking treatments on a short trip is how people end up irritated rather than improved. Tell the clinic everything else you have booked that week.

Sources

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